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- Original Article
- Detection rate and clinical impact of respiratory viruses in children with Kawasaki disease
- Ja Hye Kim, Jeong Jin Yu, Jina Lee, Mi-Na Kim, Hong Ki Ko, Hyung Soon Choi, Young-Hwue Kim, Jae-Kon Ko
- Clin Exp Pediatr. 2012;55(12):470-473. Published online December 20, 2012
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Purpose The purpose of this prospective case-control study was to survey the detection rate of respiratory viruses in children with Kawasaki disease (KD) by using multiplex reverse transcriptase-polymerase chain reaction (RT-PCR), and to investigate the clinical implications of the prevalence of respiratory viruses during the acute phase of KD.
Methods RT-PCR assays were carried out to screen for the presence of respiratory syncytial...
- Regional differences in phylogenetic group of
Escherichia coli strains isolated from children with urinary tract infection in Korea - Ui-Yoon Choi, Seung Beom Han, Soo Young Lee, Jin Han Kang, Sun Mi Kim, Sang Hyuk Ma
- Clin Exp Pediatr. 2012;55(11):420-423. Published online November 23, 2012
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Purpose We phylogenetically analyzed the
Escherichia coli strains isolated from children with urinary tract infection (UTI) in 2 regions of Korea. Virulence factors (VFs) and antibiotic resistance of the strains were also determined to compare the possible differences.Methods A total of 138
E. coli strains were collected from the 2 regions; Gyeongin (78 strains) and Gyeongnam (60 strains). The phylogenetic groups were...
- Review Article
- Renal scar formation after urinary tract infection in children
- Young Seo Park
- Clin Exp Pediatr. 2012;55(10):367-370. Published online October 29, 2012
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Urinary tract infection (UTI) is a common bacterial illness in children. Acute pyelonephritis in children may lead to renal scarring with the risk of later hypertension, preeclampsia during pregnancy, proteinuria, and renal insufficiency. Until now, vesicoureteral reflux (VUR) has been considered the most important risk factor for post-UTI renal scar formation in children. VUR predisposes children with UTI to pyelonephritis,...
- Case Report
- A case of reactive arthritis after
Salmonella enteritis in in a 12-year-old boy - Peter Chun, Young Jin Kim, Young Mi Han, Young Mi Kim
- Clin Exp Pediatr. 2011;54(7):313-315. Published online July 31, 2011
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Reactive arthritis comprises a subgroup within infection-associated arthritides in genetically susceptible hosts. Researchers and clinicians recognize two clinical forms of reactive arthritis which occurs after genitourinary tract infection and after gastrointestinal tract infection. Chlamydia infection has been implicated as the most common agent associated with post-venereal reactive arthritis. Studies have proposed Shigella infection,
Salmonella infection, orYersinia infection as the...
- Original Article
- Antibiotic susceptibility and imaging findings of the causative microorganisms responsible for acute urinary tract infection in children: a five-year single center study
- Ji Eun Yoon, Wun Kon Kim, Jin Seok Lee, Kyeong-Seob Shin, Tae-Sun Ha
- Clin Exp Pediatr. 2011;54(2):79-85. Published online February 28, 2011
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Purpose We studied the differences in the antibiotic susceptibilities of the microorganisms that causeing urinary tract infections (UTI) in children to obtain useful information on appropriate drug selection for childhood UTI.
Methods We retrospectively analyzed the antibiotic susceptibilities of 429 microorganisms isolated from 900 patients diagnosed with UTI in the Department of Pediatrics, Chungbuk National University Hospital, from 2003 to 2008.
Results The most common...
- Clinical manifestations of CNS infections caused by enterovirus type 71
- Cheol Soon Choi, Yun Jung Choi, Ui Yoon Choi, Ji Whan Han, Dae Chul Jeong, Hyun Hee Kim, Jong Hyun Kim, Jin Han Kang
- Clin Exp Pediatr. 2011;54(1):11-16. Published online January 31, 2011
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Purpose Enterovirus 71, one of the enteroviruses that are responsible for both hand-foot-and-mouth disease and herpangina, can cause neural injury. During periods of endemic spread of hand-foot-andmouth disease caused by enterovirus 71, CNS infections are also frequently diagnosed and may lead to increased complications from neural injury, as well as death. We present the results of our epidemiologic research on the...
- Case Report
- Transient splenial lesion of the corpus callosum in a case of benign convulsion associated with rotaviral gastroenteritis
- Yoon Young Jang, Kye Hyang Lee
- Clin Exp Pediatr. 2010;53(9):859-862. Published online September 13, 2010
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Transient magnetic resonance (MR) signal changes in the splenium of the corpus callosum (SCC) arise from many different conditions, including encephalopathy or encephalitis caused by infection, seizures, metabolic derangements, and asphyxia. Few case reports exist on reversible SCC lesions associated with rotavirus infection. A benign convulsion with mild gastroenteritis (CwG) is frequently associated with rotaviral infections. This entity is characterized...
- Original Article
- Microalbuminuria in children with urinary tract infection
- Byung Ok Kwak, Sochung Chung, Kyo Sun Kim
- Clin Exp Pediatr. 2010;53(9):840-844. Published online September 13, 2010
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Purpose Microalbuminuria is defined as increased urinary albumin excretion (30-300 mg/day) or microalbumin/creatinine ratio (30-300 mg/g) in a spot urine sample. Although microalbuminuria is a predictor of clinical nephropathy and cardiomyopathy, few studies have investigated microalbuminuria in children with urinary tract infection (UTI).
Methods Therefore, we compared the spot urine microalbumin/creatinine ratio in pediatric UTI patients with that of control subjects. We investigated...
- Clinical characteristics of acute lower respiratory tract infections due to 13 respiratory viruses detected by multiplex PCR in children
- Jeong-Sook Lim, Sung-Il Woo, Hyuk-Il Kwon, Hyuk-Il Kwon, Young-Ki Choi, Youn-Soo Hahn
- Clin Exp Pediatr. 2010;53(3):373-379. Published online March 15, 2010
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Purpose : This study was performed to investigate the epidemiologic and clinical features of 13 respiratory viruses in children with acute lower respiratory tract infections (ALRIs). Methods : Nasopharyngeal aspirates were prospectively obtained from 325 children aged 15 years or less from May 2008 to April 2009 and were tested for the presence of 13 respiratory viruses by multiplex real-time-polymerase chain... -
- The relationships between clinical variables and renal parenchymal disease in pediatric clinically suspected urinary tract infection
- Jung Lim Byun, Sang Taek Lee, Sochung Chung, Kyo Sun Kim
- Clin Exp Pediatr. 2010;53(2):222-227. Published online February 15, 2010
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Purpose : To evaluate the significance of clinical signs and laboratory findings as predictors of renal parenchymal lesions and vesicoureteral reflux (VUR) in childhood urinary tract infection (UTI). Methods : From July 2005 to July 2008, 180 patients admitted with a first febrile UTI at the Pediatric Department of Konkuk University Hospital were included in this study. The following were... -
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- Association between Kawasaki disease and acute respiratory viral infections
- Eun Young Cho, Byung Wook Eun, Nam Hee Kim, Jina Lee, Eun Hwa Choi, Hoan Jong Lee, Jung Yun Choi
- Clin Exp Pediatr. 2009;52(11):1241-1248. Published online November 15, 2009
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Purpose : The etiology of Kawasaki disease (KD) is still unknown. Recently, an association between human coronavirus NL63 (HCoV-NL63) and KD was implicated. Hence, we attempted to determine the association between KD and acute respiratory viral infections. Methods : Nasopharyngeal aspirate samples were obtained from 54 patients diagnosed with KD at the Seoul National University (SNU) Children’s Hospital and SNU-Bundang Hospital... -
- Microbiological spectrum and antibiotic susceptibility pattern in more than 24-month-old children with urinary tract infection: A6-year retrospective, single center experience
- Jeong Hee Ko, Jee Hyung Lee, Eun Jung Shim, Do jun Cho, Ki Sik Min, Ki Yang Yoo, Dae Young Lee, Hee Jung Kang
- Clin Exp Pediatr. 2009;52(10):1147-1152. Published online October 15, 2009
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Purpose : To characterize the pathogens and their antibiotic susceptibilities in more than 24-month-old children with urinary tract infection (UTI) and to study the Escherichia coli antimicrobial susceptibility trend. Methods : We retrospectively reviewed the record of more than 24-month-old children with UTI between January 2003 and December 2008. Positive results for 1 bacterial species with a colony count of... -
- Comparative study of newborns of Asian immigrant and Korean women
- Hee-ok Park, Jae-woo Lim, Hyun-seung Jin, Jae-won Shim, Min-hee Kim, Chun-soo Kim, Eun-ryoung Kim, Seung-youn Kim, Sang-kee Park, Jung-joo Lee
- Clin Exp Pediatr. 2009;52(10):1119-1126. Published online October 15, 2009
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Purpose : This study compares the maternal characteristics and birth outcomes of infants of Asian immigrant mothers from developing countries with those of the infants of Korean mothers. Methods : In this multicenter and retrospective study, Asian immigrant women who had delivered between January 2005 and June 2008 were enrolled from9 Medical Centers. In all, 333 births to Asian immigrant... -
- Case Report
- A case of adolescent Kawasaki disease with Epstein-Barr virus-associated infectious mononucleosis complicated by splenic infarction
- Byeong Sam Choi, Bo Sang Kwon, Gi Beom Kim, Yoon Kyung Jeon, Jung-Eun Cheon, Eun Jung Bae, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
- Clin Exp Pediatr. 2009;52(9):1029-1034. Published online September 15, 2009
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Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology that affects children. There are few reports that describe the Epstein-Barr virus (EBV) as the possible infectious agent of KD. Here, we describe a case of KD in a 15- year-old boy complicated with giant coronary artery aneurysms, pericardial effusion, and splenic infarction. The clinical course of KD was... -
- Review Article
- Guidelines for childhood urinary tract infection
- Seung Joo Lee
- Clin Exp Pediatr. 2009;52(9):976-983. Published online September 15, 2009
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Urinary tract infection (UTI), the most common bacterial disease in childhood, is frequently associated with urinary tract anomalies (15-50%) and can induce renal scarring, which is a cause of hypertension and chronic kidney disease. Despite the high risk of renal scarring in infancy, the diagnosis may be delayed due to its nonspecific presenting symptoms; moreover, over-diagnosis is frequent due to... -
- Original Article
- Clinical study of urinary tract infection, natural courses, and prenatal ultrasonographic results according to the grades of hydronephrosis
- Jee-Hee Lee, Jun-Woo Kim, Ji-Eun Yoon, Tae-Sun Ha
- Clin Exp Pediatr. 2009;52(8):917-921. Published online August 15, 2009
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Purpose:Although renal ultrasonography (USG) has improved the detection rate of hydronephrosis (HN), its clinical courses and postnatal management remains controversial. Here, we reviewed the clinical features of patients with HN according to the grades. Methods:We retrospectively studied 207 patients who were regularly followed-up among 367 patients with HN detected by renal USG postnatally between April 1998 and December 2007. These patients were grouped... -
- Predictive factors for severe infection among febrile infants younger than three months of age
- Eun Young Cho, Hwa Song, Ae Suk Kim, Sun Ju Lee, Dong Seok Lee, Doo Kwun Kim, Sung Min Choi, Kwan Lee, Byoung Chan Park
- Clin Exp Pediatr. 2009;52(8):898-903. Published online August 15, 2009
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Purpose:This study investigated the predictive factors for identifying infection-prone febrile infants younger than three months. Methods:We conducted a retrospective study of 167 infants younger than three months with an axillary temperature >38℃ who were hospitalized between 2006 and 2008. If they met any of the following criteria, positive blood culture, CSF WBC ≥ 11/mm3 or positive CSF culture, urinalysis WBC ≥6/HPF and positive... -
- Salmonellosis in children: Analysis of 72 Salmonella-positive culture cases during the last 10 years
- Sung Hoon Noh, Ka Young Yu, Jung Soo Kim, Pyoung Han Hwang, Dae Sun Jo
- Clin Exp Pediatr. 2009;52(7):791-797. Published online July 15, 2009
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Purpose : We aimed to investigate the clinical manifestations of and antibiotic resistance in culture-proven childhood salmonellosis. Methods : Clinical manifestations and laboratory data of and antibiotic use in subjects with culture-proven childhood salmonellosis, who were treated at the Chonbuk National University Hospital between September 1998 and August 2008, were analyzed retrospectively. Patients with underlying diseases or concomitant illnesses were excluded. Results... -
- Case Report
- A Korean familial case of hereditary complement 7 deficiency
- Moon Kyu Ki, Kyung Yul Lee, Jun Hwa Lee
- Clin Exp Pediatr. 2009;52(6):721-724. Published online June 15, 2009
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Meningococcal infections can be associated with abnormalities of the complement system, which contains 5 terminal complement proteins. Furthermore, deficiencies in 1 of these 5, complement component 7 (C7), leads to the loss of complement lytic function, and affected patients show increased susceptibility to recurrent meningococcal meningitis and systemic Neisseria gonorrhoeae infection. In September 2003, an 11-year-old female patient presented at... -
- Original Article
- Clinical significance of codetection of the causative agents for acute respiratory tract infection in hospitalized children
- Eui Jung Roh, Young Pyo Chang, Jae Kyung Kim, In Soo Rheem, Kwi Sung Park, Eun Hee Chung
- Clin Exp Pediatr. 2009;52(6):661-666. Published online June 15, 2009
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Purpose : To determine the prevalence and clinical features of codetected respiratory etiological agents for acute respiratory infection in hospitalized children. Methods : Nasopharyngeal aspirates were obtained from hospitalized children with acute respiratory infection at Dankook University Hospital from September 2003 through June 2005. Immunofluorescent staining and culture were used for the detection of respiratory viruses (influenza virus [IFV] types... -
- Review Article
- Treatment of latent tuberculous infection in children and adolescent
- Jong-Hyun Kim
- Clin Exp Pediatr. 2009;52(5):519-528. Published online May 15, 2009
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Tuberculosis continues to cause an unacceptably high toll of disease and death among children worldwide. Whereas intense scientific and clinical research efforts into novel diagnostic, therapeutic, and preventive interventions have focused on tuberculosis in adults, childhood tuberculosis has been relatively neglected. However, children are particularly vulnerable to severe disease and death following infection, and those with latent infection become the... -
- Case Report
- A case of fatal pneumococcal 19A meningoencephalitis despite administration of seven-valent pneumococcal conjugate vaccines
- Ah Rum Heo, Jun Hwa Lee
- Clin Exp Pediatr. 2009;52(4):508-511. Published online April 15, 2009
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Streptococcus pneumoniae is a major cause of serious invasive diseases in children, especially in young infants, but seven- valent pneumococcal conjugate vaccine (PCV7) is believed to prevent invasive pneumococcal pneumonia and meningitis in young children. However, recently, the incidence of non-PCV7 serotype has increased after PCV7 vaccination. A 14-month- old female patient presented at our emergency room with mental change... -
- Original Article
- Factors affecting the contamination of bag urine culture in febrile children under two years
- Wook Hyun Choi, In Seok Lim
- Clin Exp Pediatr. 2009;52(3):346-350. Published online March 15, 2009
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Purpose : Since children under two years with suspected urinary tract infections (UTIs) cannot control urination, urine cultures in such children are usually performed via urine bags. This method is noninvasive but has a high contamination rate. We studied the contamination rate of bag urine culture in diagnosing UTI in infants under two years and the factors responsible for contamination. Methods... -
- Epidemiologic and clinical features in children with acute lower respiratory tract infection caused by human metapneumovirus in 2006-2007
- Gwi Ok Park, Ji Hyun Kim, Jae Hee Lee, Jung Ju Lee, Sin Weon Yun, In Seok Lim, Dong Keun Lee, Eung Sang Choi, Byoung Hoon Yoo,, Mi Kyung Lee, Soo Ahn Chae
- Clin Exp Pediatr. 2009;52(3):330-338. Published online March 15, 2009
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Purpose : The causes of acute lower respiratory tract infection (ALRTI) are mostly attributable to viral infection, including respiratory syncytial virus (RSV), parainfluenza virus (PIV), influenza virus A/B (IFV A/B), or adenovirus (ADV). Several Korean studies reported human metapneumovirus (hMPV) as a common pathogen of ALRTI. However, studies on seasonal distribution and clinical differences relative to other viruses are insufficient,... -
- Review Article
- Acute viral lower respiratory tract infections in children
- Joon Soo Park
- Clin Exp Pediatr. 2009;52(3):269-276. Published online March 15, 2009
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Viruses are the most common cause of lower respiratory tract infections (LRTIs) in infants and young children and are a major public health problem in this age group. Viruses were identified in 54.9-70.4% of hospitalized infants and children with LRTIs in Korea. The viral pathogens identified included respiratory syncytial virus (RSV) A and RSV B, influenza (Inf) A, Inf B,... -
- Original Article
- Rotavirus-associated neonatal necrotizing enterocolitis
- Hyun Joo Seo, Yu Jin Jung, Soo Kyung Park, Seo Hui Choi, Ji Hyuk Lee, Myo Jing Kim, Yun Sil Chang, Won Soon Park
- Clin Exp Pediatr. 2009;52(1):56-60. Published online January 15, 2009
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Purpose : This study aimed to test whether rotavirus-associated necrotizing enterocolitis (RV+NEC) produced different clinical findings or outcomes from those of non-rotavirus necrotizing enterocolitis (RV-NEC). Methods : Eight patients from the RV+NEC group and 22 patients from the RV-NEC group diagnosed with modified Bell stage II or higher NEC were selected for this study. Fecal specimens from all infants were tested... -
- Clinical characteristics of Epstein-Barr virus infection detected by polymerase chain reaction in children less than 15 years old
- Jong-In Na, Ok Lan Kim, Do-kyoung Seoung, Seong-Taek Yoo, Chang Woo Lee, Doo-Young Choi, Yeon-Kyun Oh, Ji-Hyun Cho, Jong-Duck Kim
- Clin Exp Pediatr. 2008;51(11):1191-1197. Published online November 15, 2008
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Purpose : Previously, Epstein-Barr virus (EBV) infection was diagnosed by serological examination; currently, many EBV antigen detection methods have been developed and applied clinically for diagnosing EBV infection. To delineate the clinical characteristics of EBV infection, clinical and laboratory findings were evaluated for patients who tested positive in EBV polymerase chain reaction (PCR). Methods : EBV PCR was conducted in 352... -
- Detection and clinical manifestations of twelve respiratory viruses in hospitalized children with acute lower respiratory tract infections : Focus on human metapneumovirus, human rhinovirus and human coronavirus
- Kum Hyang Kim, Jung Ho Lee, Dong Shin Sun, Dong Shin Sun, Young Jin Choi, Joon Soo Park, Chang Jin Kim, Dong Jun Jung
- Clin Exp Pediatr. 2008;51(8):834-341. Published online August 15, 2008
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Purpose : This study was perfomed to analyze in detail the viral etiology of acute lower respiratory tract infections (ALRI) in Cheunan, Korea by multiplex RT-PCR, including human rhinovirus (hRV) and newly identified viruses such as human metapneumovirus (hMPV) and human coronavirus (HCoV-OC43, HCoV-229E/NL63). Method : Nasopharyngeal aspirates (NPA) were collected from 863 hospitalized children with ALRI on the first day... -
- Chlamydia trachomatis respiratory infection in Korean young infants
- Ki Bae Hong, Youn Shim Shin, Eui-Jung Roh, Eun Hee Chung
- Clin Exp Pediatr. 2008;51(7):729-735. Published online July 15, 2008
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Purpose : Chlamydia trachomatis is one of the most common sexually transmitted diseases and is also a cause of pneumonia in infants. Respiratory infections by respiratory viruses are also common for infants. The objectives of this study were to identify the clinical manifestations and to determine the prevalence of C. trachomatis respiratory infections and coinfections by respiratory viruses in infants... -
- Case Report
- A case of lethal kwashiorkor caused by feeding only with cereal grain
- Hyun Ju Lee, Kyung Hye Km, Hye Jin Park, Kye Hyang Lee, Gyeong Hoon Lee, Eun Jin Choi, Jin Kyung Kim, Hai Lee Chung, Woo Taek Kim
- Clin Exp Pediatr. 2008;51(3):329-334. Published online March 15, 2008
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Kwashiorkor is a syndrome of severe protein malnutrition, which manifests itself in hypoalbuminemia, diarrhea, dermatitis, and edema. It can be life-threatening due to associated immune deficiency and an increased susceptibility to infections. Kwashiorkor should be treated early with nutritional support and the control of infection. Dilated cardiomyopathy may develop during the treatment and in such cases a poor prognosis is... -
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Impact Factor4.2
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6.52022CiteScore92nd percentilePowered by
